Value of ALBI, PALBI classification in assessment of liver function in patients with hepatocellular carcinoma with cirrhosis at Nghe An Friendship General Hospital

Abstract

Objectives: To assess the relationship between ALBI and PALBI grades with clinical and subclinical characteristics in patients with hepatocellular carcinoma (HCC) with cirrhosis at Nghe An Friendship General Hospital. Participants and Methods: A cross-sectional descriptive study on 82 patients diagnosed with cirrhosis and confirmed hepatocellular carcinoma at Nghe An General Friendship Hospital from January 2020 to June 2021. Results: The age group is mainly from 50 - 69 years old (63.4%); Male/Female ratio = 3.54/1; The rate of esophageal varices levels: non-varicose, 1,2,3 grade were 59.8%, 26.8%, 8.5% and 4.9%, respectively; The rate of Child-pugh A, B, C are: 73.2%, 20.7% and 6.1%, respectively; The rate of ALBI of grades 1,2,3 is 54.9%, 32.9% and 12.2% respectively; The PALBI-1 subgroup was the majority with 41.5%; PALBI-2,3 together accounted for 29.3%; There is a meaning correlation between ALBI, PALBI index and BCLC stage (Barcelona Clinic Liver Cancer); The threshold value of PALBI for diagnosis of esophageal varices is -2.219 with a sensitivity of 66.7% and a specificity of 83.7%. Conclusion: PALBI and ALBI grade are good, simple tools for assessing the stage, severity, and risk of esophageal varices in HCC patients with cirrhosis. Key words: PALBI, ALBI, HCC,cirrhosis.