Valuation of the EQ-5D-3L in Russia

Fredrick Dermawan Purba,Tatiana Bezdenezhnykh,Bram Roudijk,Nuriya Musina,Vitaly Omelyanovskiy,Vlada Fediaeva,Svetlana Ratushnyak

doi:10.1007/s11136-021-02804-6

Abstract

PurposeThe most widely used generic questionnaire to estimate the quality of life for yielding quality-adjusted life years in economic evaluations is EQ-5D. Country-specific population value sets are required to use EQ-5D in economic evaluations. The aim of this study was to establish an EQ-5D-3L value set for Russia.MethodsA representative sample aged 18+ years was recruited from the Russia`s general population. Computer-assisted face–to–face interviews were conducted based on the standardized valuation protocol using EQ-Portable Valuation Technology. Population preferences were elicited utilizing both composite time trade-off (cTTO) and discrete choice experiment (DCE) techniques. To estimate the value set, a hybrid regression model combining cTTO and DCE data was used.ResultsA total of 300 respondents who successfully completed the interview were included in the primary analysis. 120 (40.0%) respondents reported no health problems of any dimension, and 56 (18.7%) reported moderate health problems in one dimension of the EQ‐5D‐3L. Median self-rated health using EQ‐VAS was 80 with IQR 70–90. Comparing cTTO and DCE-predicted values for 243 health states resulted in a similar pattern. This supports the use of hybrid models. The predicted value based on the preferred model for the worst health state “33333” was −0.503. Mobility dimension had the most significant impact on the utility decrement, and anxiety/depression had the lowest decrement.ConclusionDetermining a Russian national value set may be considered the first step towards promoting cost-utility analysis use to increase comparability among studies and improve the transferability of healthcare decision-making in Russia.

Highlights

Over the last few years, health technology assessment (HTA) has been increasingly utilized to provide input into the national health policy decision-making process in Russia
With the Order of the Government of Russia, No 871, adopted in 2014, HTA is required for making policy decisions on whether to include new pharmaceuticals or to exclude those already provided, in the list of drugs funded under State Guarantees Program or the federal budget [1]
The EQ-5D-3L questionnaire was selected to elicit the preferences of Russia’s general population with the aim to establish an EQ-5D-3L value set for Russia

Summary

Introduction

Over the last few years, health technology assessment (HTA) has been increasingly utilized to provide input into the national health policy decision-making process in Russia. With the Order of the Government of Russia, No 871, adopted in 2014, HTA is required for making policy decisions on whether to include new pharmaceuticals or to exclude those already provided, in the list of drugs funded under State Guarantees Program or the federal budget [1]. HTA is a transparent way of choosing how to allocate these available resources to achieve maximum healthcare benefits. The real costs of this technology would not be the money spent on it, but the healthcare benefits which would be lost, namely the “opportunity costs” [2].

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