Abstract
Valproic acid (VPA) is a widely used drug in the field of neuro-pschiatry for the treatment of various types of epilepsy, as prophylaxis for migraine headaches, and in the treatment and prevention of manic attacks related to bipolar disorder. Ototoxicity related to VPA is very rare and only a few cases have been reported in the literature. In this case report, a 21-year old male patient admitted to our clinic with the complaint of bilateral sudden total hearing loss associated with VPA is presented. The patient had a history of moderate hearing loss before initiation of VPA and on the second day of his VPA treatment, a further reduction in his hearing levels occurred. At the end of the third day, the total hearing loss had developed which did not respond to treatment and became permanent.
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