Abstract
Valproate-induced hyperammonemic encephalopathy is a rare event clinically characterized by altered sensorium, vomiting, headache, irritability and focal neurological decits. The pathogenesis of this dreadful complication is not well understood, although hyperammonemia has been implicated in causation of encephalopathy. In this case report, we bring to light a case of valproate-induced encephalopathy who presented mainly with difculty in walking and speech, body tremelousness. High index of suspicion of valproate-induced hyperammonemic encephalopathy is required if diffuse ataxia is present as it is a potentially reversible clinical disorder.
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