Abstract
ObjectiveTo determine the predictive value of 24-hour proteinuria in neonatal outcome in preeclamptic patients. Materials and methodsWe selected 87 preeclamptic patients attending the Accident and Emergency Department of the Dr. Urquinaona Central Hospital, in Maracaibo, Venezuela. General characteristics, 24-hour proteinuria values, and neonatal outcome were evaluated. ResultsThe mean age of patients was 26.0±5.4 years. Gestational age at diagnosis was 32.9±3.3 weeks. The mean value of 24-hour proteinuria was 4.5±1.8 grams. When proteinuria was separated in quartiles depending on concentration (low, moderate, high and extremely high), we observed that lower values of neonatal weight corresponded to groups of high and extremely high concentrations compared with the group with low concentrations (P<.05). No significant differences were found among groups in neonatal complications and mortality (P=ns). A cut-off of 3 grams for 24-hour proteinuria did not show an area below the curve higher than 0.70, the value necessary to be significant, nor was this value significant (P=ns) in predicting neonatal complications and mortality (P=ns). ConclusionThis study did not find that 24-hour proteinuria had any value in predicting neonatal outcomes in preeclamptic patients.
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