Abstract
The article by Liese et al. (1) investigated the association of glycemic index, glycemic load, and total carbohydrate and fiber intake with direct measures of insulin sensitivity, insulin secretion, and adiposity in a cohort of 979 adults with normal and impaired glucose tolerance. The authors concluded that there were no significant associations of glycemic index, glycemic load, and carbohydrate intake with any measure of insulin sensitivity or secretion. In their study, usual dietary intake was assessed via a 114-item food frequency questionnaire (FFQ) that had been previously “validated” in a subsample of the Insulin Resistance Atherosclerosis Study (IRAS) population. Unfortunately, …
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