Abstract

Objective To investigate the association between carotid atherosclerosis and coronary atherosclerosis in ischemic stroke/transient ischemic attack (TIA) patients using color Doppler ultrasound. Methods A total of 165 patients with first episode of atherothrombosis (AT)/TIA patients were enrolled from August 2014 to August 2015 in our hospital; 80 patients with coronary artery diseases detected by coronary CT angiography were used as disease group, and 85 without coronary artery disease were as control group. Combining with the examination of the risk factors of atherosclerosis, the value of colored Doppler ultrasound in screening coronary atherosclerosis in ischemic stroke/TIA patients was evaluated. Results Combined with plasma low density lipoprotein and high-density lipoprotein levels, the vulnerable plaques were detected by colored Doppler ultrasound, enjoying detection of coronary atherosclerosis sensitivity of 66.25%, specificity of 76.47%, positive predictive value of 72.60% and negative predictive value of 70.65%, and accuracy of 71.5% (Wilkes' Lambda=0.856, χ2=24.881, P=0.000). Conclusion Combining with blood lipid level, vulnerable plaque can be the effective indicator for coronary atherosclerosis in patients with ischemic stroke/TIA. Key words: Coronary atherosclerosis; Ischemic stroke; Color Doppler ultrasound

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