Abstract

BackgroundFamilial history information could be useful in clinical practice. However, little is known about the accuracy of self-reported familial history, particularly self-reported familial history of obesity (FHO).MethodsTwo cross-sectional studies were conducted. The aims of study 1 was to compare self-reported and objectively measured weight and height whereas the aims of study 2 were to examine the relationship between the weight and height estimations reported by the study participants and the values provided by their family members as well as the validity of a self-reported measure of FHO. Study 1 was conducted between 2004 and 2006 among 617 subjects and study 2 was conducted in 2006 among 78 participants.ResultsIn both studies, weight and height reported by the participants were significantly correlated with their measured values (study 1: r = 0.98 and 0.98; study 2: r = 0.99 and 0.97 respectively; p < 0.0001). Estimates of weight and height for family members provided by the study participants were strongly correlated with values reported by each family member (r = 0.96 and 0.95, respectively; p < 0.0001). Substantial agreement between the FHO reported by the participants and the one obtained by calculating the BMI of each family members was observed (kappa = 0.72; p < 0.0001). Sensitivity (90.5%), specificity (82.6%), positive (82.6%) and negative (90.5%) predictive values of FHO were very good.ConclusionA self-reported measure of FHO is valid, suggesting that individuals are able to detect the presence or the absence of obesity in their first-degree family members.

Highlights

  • Familial history is a risk factor of several chronic diseases of public health significance, including obesity

  • It has been proposed that familial history information could be useful in clinical practice and construction of family pedigrees could provide important data for use in genetic studies [1,2,3]

  • Little is known about the accuracy of self-reported familial history, selfreported familial history of obesity (FHO)

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Summary

Introduction

Familial history is a risk factor of several chronic diseases of public health significance, including obesity. The accuracy of self-reported height and weight and the accuracy of family member estimates have been studied, there is still no available data on the validity of self-reported measure of FHO. This information could be of great importance for use in genetics studies and other studies such as those designed to understand differences between subjects with and without FHO. We assessed the correlation between weight and height estimations reported by a participant and the values provided by each family member (mother, father and siblings) in a cohort of 78 subjects including 199 family members (study 2). Little is known about the accuracy of self-reported familial history, self-reported familial history of obesity (FHO)

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