Abstract
There is limited documentation of using fluorescence images in oral potentially malignant disorders (OPMDs) and oral cancer screening through the field of teledentistry. This study aims to develop and evaluate the validity and reliability of the intraoral camera with the combination method of autofluorescence and LED white light used for OPMDs and oral cancer screening in teledentistry. The intraoral camera with fluorescent aids, which uses a combined method of both autofluorescence and LED white light, was developed before the device was evaluated for validity and reliability as a OPMDs screening tool for teledentistry. All lesions of thirty-four OPMD patients underwent biopsy for definitive diagnosis and were examined by an oral medicine specialist. Both images under autofluorescent and LED white light mode captured from the device were sent online and interpreted for the initial diagnosis and dysplastic features in addition to being compared to the direct clinical examination and histopathological findings. The combination method was also compared with autofluorescence method alone. The device provided good image quality, which was enough for initial diagnosis. Using the combination method, sensitivity, specificity, PPV, and NPV of the device via teledentistry were 87.5%, 84.6%, 63.6%, and 95.7%, respectively, which were higher than autofluorescence method alone in every parameter. The concordance of dysplastic lesion was 85.29% and 79.41% for category of lesion. The validity and reliability results of the combination method for the screening of dysplasia in OPMDs were higher than autofluorescent method alone. The intraoral camera with fluorescent aids for the OPMDs screening can be utilized for screening via teledentistry.
Highlights
Ninety percent of squamous cell carcinomas (SCC) are developed from oral potentially malignant disorders (OPMDs) [1]
The devices light intensity is much less than the intensity of curing light. e intraoral camera with fluorescent aids used in OPMDs and oral cancer screening can emit the maximum irradiance of blue excitation light at about 2000 Lux, 7,500 Lux for light-emitting diodes (LED) white light at the focal length of 2.5 cm from the tissue
Nine lesions were clinically diagnosed as leukoplakia, 5 lesions were clinically diagnosed as discoid lupus erythematosus, and only one lesion was clinically diagnosed as a squamous cell carcinoma
Summary
Ninety percent of squamous cell carcinomas (SCC) are developed from oral potentially malignant disorders (OPMDs) [1]. Previous studies have shown that the validity and reliability of those devices used as teledentistry tools could be comparable to conventional direct examination for oral screening [9,10,11]. There is limited documentation and investigation on the validity and reliability of using fluorescence images from an autofluorescence method in teledentistry through the field of oral medicine for OPMDs and oral cancer screening as previous studies used only images under normal white light to evaluate via teledentistry [10, 11]; fluorescence images were not yet been included. E combination method between autofluorescence and white light from light-emitting diodes (LED) could be equivalent to a conventional oral examination and autofluorescence method may increase validity for detection of epithelial dysplasia There is limited documentation and investigation on the validity and reliability of using fluorescence images from an autofluorescence method in teledentistry through the field of oral medicine for OPMDs and oral cancer screening as previous studies used only images under normal white light to evaluate via teledentistry [10, 11]; fluorescence images were not yet been included. e combination method between autofluorescence and white light from light-emitting diodes (LED) could be equivalent to a conventional oral examination and autofluorescence method may increase validity for detection of epithelial dysplasia
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
