Year-end Sale % OFF 
Abstract
Block Copolymer Self-assembled and Cross-linked Nanoassemblies for Combination Delivery of Iron Oxide and DoxorubicinDaniel Scott, Yihwa Beabout , Robert J. Wydra, Mo Dan, Robert Yokel, J. Zach Hilt and Younsoo Bae
Highlights
Salmeterol xinafoate (SAL); (RS)-5-salicyl alcohol 1hydroxy-2-naphthoate and Fenoterol hydrobromide (FEN);1(3,5-Dihydroxyphenyl)-2 -(4-hydroxy-α-methylphenethylamino) ethanol hydrobromide, are selective beta-2 agonist drugs that are widely used for the treatment of Asthma and chronic obstructive pulmonary diseases due to their direct sympathomimetic action on the smooth muscles (Martindale, 2005)
We utilized the presence of phenolic and hydroxyl groups in the studied drugs to quantitatively reduce the Fe (III) in the Fe (III)-o-Phenanthroline complex toform stable red colored chromogen corresponding to Fe (II) o-Phenanthroline complex (Fig 2) that can be measured spectrophotometrically at 510 nm, Fig 3
Linearity and concentration range In this work, the general analytical procedure was performed on a series of standard drug solutions having concentrations ranging from (0.7-7.0) and (1.0-8.0) μg.mL-1 for Salmeterol and Fenoterol, respectively.The whole set of experiments were carried out within this range to ensure the validation of the proposed procedure
Summary
Salmeterol xinafoate (SAL); (RS)-5-salicyl alcohol 1hydroxy-2-naphthoate and Fenoterol hydrobromide (FEN);1(3,5-Dihydroxyphenyl)-2 -(4-hydroxy-α-methylphenethylamino) ethanol hydrobromide, are selective beta-2 agonist drugs that are widely used for the treatment of Asthma and chronic obstructive pulmonary diseases due to their direct sympathomimetic action on the smooth muscles (Martindale, 2005). A Simple, accurate and sensitive spectrophotometric method has been established and validated for the determination of two selective beta-2 agonist drugs namely; Salmeterol xinafoate and Fenoterol hydrobromide in their pure forms and pharmaceutical preparations.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
