Abstract
Validation of MRI in the Assessment of Tophaceous Gout: An Imaging Panegyric
Highlights
Magnetic Resonance Imaging [MRI] allows assessing the presence of joint deposits of Monosodium Urate [MSU] and bone erosions in patients with tophaceous gout
MRI is especially useful in patients with solitary tophi, without joint disease, who can pose a differential diagnosis with neoplastic processes, pigmented villonodular synovitis, and granulomatous diseases such as mycosis or tuberculosis, or in tophi with an important inflammatory reaction that can mimic septic arthritis or an osteomyelitis [1,2,3,4,5,6]
104 tophi were evaluated with the mean of the maximum diameter of the tophi in LL, AP and CC of 13, 20 and 26 mm respectively
Summary
Magnetic Resonance Imaging [MRI] allows assessing the presence of joint deposits of Monosodium Urate [MSU] and bone erosions in patients with tophaceous gout. It allows the detection of associated structural lesions, such as meniscus or ligament pathology, which can be confusing with chronic symptoms associated with urate deposition [1,2]. MRI after intravenous infusion of gadolinium facilitates the study of inflammatory changes of the synovial membrane [3]. After administration of intravenous contrast, an enhancement can be visualized around the nodular image, called corona, due to the increase in vascularization associated with the granulation tissue [7]
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