Abstract

The validation of the method of metronidazole polarographic determination in infusion solutions has been performed. This method is based on the reduction of the nitro group of metronidazole on the mercury dropping electrode. The main validation parameters such as the specificity, the robustness, the linearity, the accuracy as well as the precision have been determined within the used method. The technique conforms the current requirements for the methods of quantification of substances in medical products. Keywords: polarography, metronidazole, nitro group, antibiotic, validation.

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