Abstract
BackgroundThe objective of this study was to evaluate the validity of self reported criteria of Metabolic Syndrome (MS) in the SUN (Seguimiento Universidad de Navarra) cohort using their medical records as the gold standard.MethodsWe selected 336 participants and we obtained MS related data according to Adult Treatment Panel III (ATP III) and International Diabetes Federation (IDF). Then we compared information on the self reported diagnosis of MS and MS diagnosed in their medical records. We calculated the proportion of confirmed MS, the proportion of confirmed non-MS and the intraclass correlation coefficients for each component of the MS.ResultsFrom those 336 selected participants, we obtained sufficient data in 172 participants to confirm or reject MS using ATP III criteria. The proportion of confirmed MS was 91.2% (95% CI: 80.7- 97.1) and the proportion of confirmed non-MS was 92.2% (95% CI: 85.7-96.4) using ATP III criteria. The proportion of confirmed MS using IDF criteria was 100% (95% CI: 87.2-100) and the proportion of confirmed non-MS was 97.1% (95% CI: 85.1-99.9). Kappa Index was 0.82 in the group diagnosed by ATP III criteria and 0.97 in the group diagnosed by IDF criteria. Intraclass correlation coefficients for the different component of MS were: 0.93 (IC 95%:0.91- 0.95) for BMI; 0.96 (IC 95%: 0.93-0.98) for waist circumference; 0.75 (IC 95%: 0.66-0.82) for fasting glucose; 0.50 (IC 95%:0.35-0.639) for HDL cholesterol; 0.78 (IC 95%: 0.70-0.84) for triglycerides; 0.49 (IC 95%:0.34-0.61) for systolic blood pressure and 0.55 (IC 95%: 0.41-0.65) for diastolic blood pressure.ConclusionsSelf-reported MS based on self reported components of the SM in a Spanish cohort of university graduates was sufficiently valid as to be used in epidemiological studies.
Highlights
Visceral obesity, insulin resistance, high blood pressure, and dyslipidemia are some of the characteristic abnormalities of the metabolic syndrome (MS)
Part of this information is self-reported and participants obtain it from their blood test and medical check-ups that they routinely undergo in Spain by their occupational physicians
Definition of self-reported Metabolic Syndrome (MS) and confirmed MS We considered that a participant reported MS if the criteria of MS according to Adult Treatment Panel III (ATP III) criteria were present in the questionnaire
Summary
Insulin resistance, high blood pressure, and dyslipidemia are some of the characteristic abnormalities of the metabolic syndrome (MS). The association of these alterations confers a high risk of atherosclerosis and cardiovascular disease, more than the sum of the individual risks [1]. Self-reported diagnosis of MS could not be useful in populations with low cultural level but could be enough valid in a cohort of university graduates. The objective of this study was to evaluate the validity of self reported criteria of Metabolic Syndrome (MS) in the SUN (Seguimiento Universidad de Navarra) cohort using their medical records as the gold standard
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