Abstract

Purpose: Hermes workstation (Hermes Medical Solutions AB, Stockholm, Sweden) is increasingly used to assess the hepatic uptake of Technetium Mebrofenate for preoperative liver function assessment. The workstation also allows assessment of anatomical and functional liver volumes on SPECT-CT scan. The aim of the current study is to compare the agreement of the semiautomated liver segmentation for the assessment of total and segmental liver volumes with post resection liver specimen volumes using Hermes workstation. Methods: A retrospective analysis was carried out using a prospectively maintained database. A total of 144 patients underwent standard right or left hepatectomy (Brisbane 2000 nomenclature) between January 2015 and December 2016 were included. Total, resection and remnant anatomical liver volumes were measured retrospectively using Hermes workstation. Postresection volumes measured by assessment of dry weight of pathological specimen were compared with the resection volumes. The Pearson’s correlation coefficient (r) was used to calculate the linear correlation using SPSS. Results: Right hepatectomy was performed in 79% and left hepatectomy in 21% of the included patients. There was no significant inter reader variability (AO,BD) as assessed on 15 initial consecutive scans (+/-15ml). The mean TLV calculated with the Hermes Software was 1688.41±582.86. The mean specimen weight measured during the histopathological analysis was 880.4±469.38. The volume of the resection segments calculated with the Hermes software significantly correlated with the weight of the specimen, with the Pearson correlation coefficient being 0.84 (p<0.001) (Figure 1). Conclusion: Hermes workstation is a reliable, and efficient tool to measure liver anatomical segmental volumes.

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