Abstract
The liver is unique in possessing a dual blood supply. It receives approximately 80 percent of flow from the portal vein and the rest from the hepatic artery. Thus, the hepatic microvasculature receives blood from two types of afferent vessels: Portal venules and hepatic arterioles. The portal venules directly connect with the sinusoids to supply the liver parenchyma with blood rich in nutrients, but at low oxygen tension. The hepatic arterial system is not just supplementary to the portal vein. It is the primary oxygen supply to sinusoidal blood. It also supplies the bile ducts, portal venules and nerves in the portal tract.
Highlights
The liver is unique in possessing a dual blood supply
The initial flushes for livers 8-10 were performed with phosphate-buffered saline (PBS)
We describe a representative from each group, below: Liver 1 is representative of group A, four livers that were perfused with PBS at two temperatures
Summary
The liver is unique in possessing a dual blood supply. It receives approximately 80 percent of flow from the portal vein and the rest from the hepatic artery. The hepatic microvasculature receives blood from two types of afferent vessels: Portal venules and hepatic arterioles. The portal venules directly connect with the sinusoids to supply the liver parenchyma with blood rich in nutrients, but at low oxygen tension. The hepatic arterial system is not just supplementary to the portal vein. It is the primary oxygen supply to sinusoidal blood. It supplies the bile ducts, portal venules and nerves in the portal tract [1,2,3]
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