Abstract

TO THE EDITOR: In their recently published article, Yi et al 1 applied a previously published nomogram 2 that was developed in a population of 1,681 patients to a population of 734 patients. We are pleased with the excellent calibration curves that were produced from the application of the nomogram to the authors’ data. With one data point exception, all CIs cross the unity line, which denotes perfect calibration. This is particularly remarkable given that the authors divided their population into octiles of risk, despite there being only 63 events in their entire population. Given this low event rate, there are few events in each octile; we suggest the use of quartiles or quintiles would be more appropriate. Dividing their population into fewer groups with more women per group would lessen the wide CIs around each of their points. The single group of patients who did not have good calibration is intriguing. The authors 1 state that this group was small

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