Abstract

Depression constitutes a major public health problem due to its high prevalence and difficulty in diagnosis. The Hopkins Symptom Checklist-25 (HSCL-25) scale has been identified as valid, reproducible, effective, and easy to use in primary care (PC). The purpose of the study was to assess the psychometric properties of the HSCL-25 and validate its Spanish version. A multicenter cross-sectional study was carried out at six PC centers in Spain. Validity and reliability were assessed against the structured Composite International Diagnostic Interview (CIDI). Out of the 790 patients, 769 completed the HSCL-25; 738 answered all the items. Global Cronbach’s alpha was 0.92 (0.88 as calculated for the depression dimension and 0.83 for the anxiety one). Confirmatory factor analysis (CFA) showed one global factor and two correlated factors with a correlation of 0.84. Area under the curve (AUC) was 0.89 (CI 95%, 0.86–0.93%). For a 1.75 cutoff point, sensibility was 88.1% (CI 95%, 77.1–95.1%) and specificity was 76.7% (CI 95%, 73.3–79.8%). The Spanish version of the HSCL-25 has a high response percentage, validity, and reliability and is well-accepted by PC patients.

Highlights

  • Licensee MDPI, Basel, Switzerland.Depression is a common condition among adults and can lead to harmful consequences

  • The Hopkins Symptom Checklist-25 (HSCL-25) is suitable for use in primary care (PC) because of its high validity and reliability; its ergonomics make it easy to use for patients [9]

  • It is a self-report questionnaire designed to measure psychological distress based on the SCL-90 [10], a longer checklist designed by Derogatis et al The full version of the SCL-90 covers nine symptom dimensions, with 25 items belonging to the anxiety and depression ones

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Summary

Introduction

Efficacy, and reproducibility were analyzed as quantitative criteria Characteristics such as being a selfadministered questionnaire, easiness of completion for patients, and the simplicity of its interpretation were taken into account to assess the ergonomics. The HSCL-25 is suitable for use in PC because of its high validity and reliability; its ergonomics make it easy to use for patients [9] It is a self-report questionnaire designed to measure psychological distress based on the SCL-90 [10], a longer checklist designed by Derogatis et al The full version of the SCL-90 covers nine symptom dimensions, with 25 items belonging to the anxiety and depression ones. The purpose of this study was to assess the HSCL-25 psychometric properties and validate the scale’s Spanish version in a PC population

Study Design
Participants
Recruitment and Sample Size
Variables
Missing Data
Responding Process and Item Analysis
Internal Structure
Criterion Validity
Internal Consistency
A Little
Reliability
Discussion
Conclusions
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