Abstract

ObjectiveTo establish the reliability and validity of a shortened (10-item) depression scale used among HIV-positive patients enrolled in the Drug Treatment Program in British Columbia, Canada.MethodsThe 10-item CES-D (Center for Epidemiologic Studies Depression Scale) was examined among 563 participants who initiated antiretroviral therapy (ART) between August 1, 1996 and June 30, 2002. Internal consistency of the scale was measured by Cronbach’s alpha. Using the original CES-D 20 as primary criteria, comparisons were made using the Kappa statistic. Predictive accuracy of CES-D 10 was assessed by calculating sensitivity, specificity, positive predictive values and negative predictive values. Factor analysis was also performed to determine if the CES-D 10 contained the same factors of positive and negative affect found in the original development of the CES-D.ResultsThe correlation between the original and the shortened scale is very high (Spearman correlation coefficient  = 0.97 (P<0.001). Internal consistency reliability coefficients of the CES-D 10 were satisfactory (Cronbach α = 0.88). The CES-D 10 showed comparable accuracy to the original CES-D 20 in classifying participants with depressive symptoms (Kappa = 0.82, P<0.001). Sensitivity of CES-D 10 was 91%; specificity was 92%; and positive predictive value was 92%. Factor analysis demonstrates that CES-D 10 contains the same underlying factors of positive and negative affect found in the original development of the CES-D 20.ConclusionThe 10-item CES-D is a comparable tool to measure depressive symptoms among HIV-positive research participants.

Highlights

  • Depression is a major problem among people living with HIV/ AIDS [1,2]

  • HIV/AIDS Drug Treatment Program This study was conducted at the Drug Treatment Program (DTP), at the BC Centre for Excellence in HIV/AIDS, which is mandated by the provincial government to distribute antiretroviral medications free of charge to all eligible HIV-positive individuals

  • 35% of participants had an average annual income of less than $10,000, 29% did not complete high school, 28% had a history of injection drug use, 20% had an AIDS diagnosis at baseline and 23% reported suboptimal adherence ($95%) in the first year of follow-up

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Summary

Introduction

The Center for Epidemiologic Studies Depression Scale (CES-D) is one of the most common screening tests for identifying depressive symptoms in the general population [3]. The 20-item scale is a self-reported measure of an individual’s depressive feelings and behaviors in the past week. It is designed for studies ascertaining the relationship between depression and other variables. Major components of depressive symptomology are incorporated into the scale including, depressed mood, feelings of guilt and worthlessness, feelings of helplessness and hopelessness, psychomotor retardation, loss of appetite, and sleep disturbance [3]. The scale has been widely used in different cohort studies suggesting its suitability for a variety of sample populations and diverse contexts

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