Abstract

Short Retraction Notice The paper does not meet the standards of American Journal of Analytical Chemistry. The article has been retracted due to the conflicts of interests between all authors to straighten the academic record. Aim is to promote the circulation of scientific research by offering an ideal research publication platform with due consideration of internationally accepted standards on publication ethics. The Editorial Board would like to extend its sincere apologies for any inconvenience this retraction may have caused. The full retraction notice in PDF is preceding the original paper, which is marked RETRACTED.

Highlights

  • Vortioxetine is 1-[2-(2,4-Dimethylphenylsulfanyl)-phenyl]-piperazine (Figure 1), which is a novel antidepressant approved in the USA and EU for the treatment of major depressive disorder [1]

  • A sensitive and validated UPLC-S/MS method was developed to determine the concentrations of VTX and FLX in rat plasma and pharmacokinetic interaction between them was studied to supply some proposals for clinical practice

  • The current study provided the lowest Lower Limit of Quantification (LLOQ) (2.5 ng/mL) designed for the analysis of VTX and FLX, compared with earlier reported liquid chromatography methods

Read more

Summary

Other: It conflicts the interests of authors

Results of publication (only one response allowed): X are still valid. were found to be overall invalid. Results of publication (only one response allowed): X are still valid. Author's conduct (only one response allowed): honest error academic misconduct X none (It conflicts the interests of authors). History Expression of Concern: X yes, date: 2020-6-4 no Correction: yes, date: yyyy-mm-dd X no Comment: The article has been retracted due to the conflicts of interests between all authors to straighten the academic record. American Journal of Analytical Chemistry, 2020, 11, 233-259 https://www.scirp.org/journal/ajac ISSN Online: 2156-8278 ISSN Print: 2156-8251. Validated UPLC-MS/MS Method for the Simultaneous Quantification of Vortioxetine and Fluoxetine in Plasma: Application to TinhWeirisPtahraRrmatascokinetic Interaction StudyD Raniah Al-Shalabi1,2*, Mohamed Hefnawy, Haya Al-Johar, Haitham Alrabiah E 1Department of Pharmacy, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia. T 4Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt

C How to cite this paper
Introduction
Materials and Reagents
Instrumentation and Analytical Conditions
Specificity
Linearity
Precision and Accuracy
Matrix Effect
Dilution Integrity
Stability Studies
Application to Pharmacokinetic Studies
Results and Discussion
Optimization of Mass Spectrometric Conditions
E Intra-dayb
C Analyte
Comparison between the Developed Method over the Earlier
Pharmacokinetic Interaction between Vortioxetine and Fluoxetine Study
Conclusion
D Fluoxetine in Plasma by Gas Chromatography-Mass Spectrometry Using Stir Bar
D Drug Interactions with Second-Generation Antidepressants

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.