Validated method for estimation of ethamsylate by UV-spectroscopy

Abstract

For the estimation of ethamsylate in pharmaceutical tablet dosage forms an accurate, simple, efficient spectrophotometric method was developed and validated. It showed absorption maxima at 300 nm with distilled water. According to ICH guidelines, the method was validated concerning specificity, linearity, accuracy, and precision. Ethamsylate’s linearity and range were found to be 5 to 50 μg/ml, with a correlation coefficient of 0.999. The analysis's findings were verified statistically and estimation of ethamsylate was done in marketed formulation.