Abstract
ObjectiveTo establish the validity and reliability of the Anosognosia Questionnaire in Dementia (AQ-D) in individuals diagnosed with major neurocognitive disorder (MND) in the Colombian population. MethodsThe AQ-D scale was adapted and validated for MND patients in Colombia through cognitive interviews and expert review. A total of 189 pairs of participants, consisting of caregivers and patients, were included in the study and administered the AQ-D questionnaire. Structural validity, internal consistency, discriminative and concurrent criterion validity, convergent validity, and test–retest feasibility were assessed. ResultsAfter exploring three models in confirmatory factorial analysis, a four-dimension model was adopted to evaluate the validity of the AQ-D scale. The scale demonstrated good internal consistency (Cronbach's alpha and McDonald's omega above 0.7 for each dimension and the total scale), and acceptable test-retest reliability (ICC 0.73; 95% CI: 0.55-0.84). A sensibility was 80.0% and specificity 57.6% were found using a cutoff point of 10, indicating good discriminative validity (P<.05 for all cases). Additionally, positive correlations were found between the AQ-D and the Zarit and NPI scales, while negative correlations were observed with the Mini-mental and Yesavage scales. ConclusionThe AQ-D is valid and reliable for screening anosognosia in Colombian patients with MND.
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