Abstract

Abstract—Background. The Quality of Life Index for Atopic Dermatitis (QoLIAD) and the Parents' Index of Quality of Life in Atopic Dermatitis (PIQoL-AD) have been developed recently for use in adult patients with atopic dermatits (AD) and parents of pediatric AD patients, respectively. Objective. To assess the psychometric properties of the Spanish versions of both questionnaires. Methods. QoLIAD and PIQoL-AD were administered in an observational, multicentre, prospective (2 visits) study which included adult AD patients (group 1) and parents of pediatric AD patients (group 2). The Dermatology Life Quality Index (DLQI) and Psychological General Well-Being Index (IBP) were also administered. Ceiling and floor effects, internal and test-retest reliability, convergent-divergent validity, and known groups validity were assessed for both questionnaires. Results. Group 1 included 83 patients and group 2 included 153 parents. For both questionnaires, ceiling and floor effects ranged between 0% and 9.2%, Cronbach's alpha values were over 0.87 and Spearman correlation coefficients for test-retest reliability ranged between 0.88 and 0.90. Correlation coefficients among target questionnaires and validated instruments were 0.79 (QoLIAD-IBP), 0.76 (QoLIAD and DLQI) and 0.52 (PIQoL.AD and IBP). QoLIAD scores were lower in patients reporting a worse overall health and self-perceived severity; while PIQoL-AD scores were lower in patients reporting a worse overall health. QoLIAD scores were worse in adult patients whose face were affected; while PIQoL-AD scores were worse in patients whose hands were affected. Conclusions. The Spanish versions of the QoLIAD and PIQoL-AD questionnaires have shown a satisfactory reliability and validity for use in this population.

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