Abstract
<h4>EXCERPT </h4> <p>In July 2005, vagus nerve stimulation (VNS) therapy was approved by the U.S. Food and Drug Administration for the adjunctive long-term treatment of chronic or recurrent depression for patients age 18 and older who are experiencing a major depressive episode and have not had an adequate response to four or more adequate antidepressant treatments. In this article, I describe the clinical studies of VNS for treatment-resistant depression (TRD), as well as preliminary studies investigating its use for other neuropsychiatric disorders. </p>
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