Abstract
ACUTE gastroduodenal ulceration occurring in association with major illness,<sup>1,2</sup>burns<sup>3</sup>(Curling's ulcer), or central nervous system trauma<sup>4-6</sup>(Cushing's ulcer) is generally referred to as "stress ulceration." Although the exact mechanism of their development is unknown, the lesions are characteristically shallow ulcers or erosions, often multiple, and without surrounding induration or microscopic evidence of chronic inflammatory response. Most often the erosions occur in the stomach or duodenum,<sup>1,3</sup>but they have been described in the distal esophagus,<sup>4,5</sup>small bowel,<sup>2</sup>and colon.<sup>6</sup>In some instances the stress ulcers produce no clinical manifestations or their presence is masked by the primary illness or injury which leads to their development, and they are discovered only at autopsy. More frequently, the sudden onset of upper gastrointestinal hemorrhage or the signs of peritonitis from perforation heralds the development of acute gastroduodenal ulceration. These complications imposed on a patient who is
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
