Vaginal Vault High-Dose-Rate Brachytherapy Alone as Adjuvant Treatment of Early-Stage Endometrial Cancer: A Retrospective Study on 119 Patients

Abstract

(DSS). Age-adjusted Charlson Comorbidity Score (HR 1.2, p Z 0.003), LVSI (HR 3.1, p Z 0.003), and RT (HR 0.43, p Z 0.01) were retained in the multivariate model for OS. Conclusions: Adjuvant RT appears to reduce the risk of local-regional failure and improve OS in this cohort of patients with early stage Type II endometrial cancer. However, distant failure is a challenge for women with type II endometrial cancer. Further investigation into optimal adjuvant systemic therapy in these patients appears justified. Author Disclosure: S. Vance: None. N. Rasool: None. M. Mahan: None. M.A. Elshaikh: None.