Abstract
Background: Preterm premature rupture of membranes (PROM) , refers to rupture of membranes before the onset of labour in women with a pregnancy 0.05). There was statistical significant difference between the two groups as regard history of PROM with higher cases in control group , gestational age at delivery (weeks) with higher percentage in study group and latency period with highly period in study group (p- value <0.05). Also, in the present study as regard neonatal outcome there were significant statistical differences between the two groups as regard 1 and 5-minute APGAR score after birth with highest low score in control group . Conclusion: This study demonstrated that the efficacy of a vaginal probiotic formula in combination with standard antibiotic prophylaxis on perinatal outcome in cases of PPROM before 34 weeks of gestation as compared to those treated only with antibiotics.
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