Vaginal Microenvironment Imbalance and Its Influence on HPV, Multiple Infections, and Cervical Lesions in the Elderly

Abstract

The vaginal microenvironment in elderly women undergoes dysregulation due to changes in the endocrine and immune systems, thereby increasing the risk of persistent HPV infection, multiple infections, cervical lesions, and related issues. These challenges have become a focal point in clinical attention. This study aims to analyze the role of vaginal microenvironment dysregulation in the development of persistent HPV infection, multiple infections, and cervical lesions. Additionally, it seeks to explore interventions targeting the vaginal microenvironment in older women. Using a literature review method and comparative analysis, this study examines the relationship between vaginal microenvironment disorders and persistent HPV infection, multiple infections, and cervical lesions in middle-aged and elderly women. It comprehensively compares the efficacy of various interventions. According to the literature review and comparative analysis, the vaginal microenvironment is closely linked to persistent HPV infection, multiple infections, and cervical lesions in elderly women. Simultaneously, this paper explores interventions for the vaginal microenvironment in the elderly. It reveals that the vaginal microenvironment in older women can be effectively addressed through local hormone replacement therapy, active probiotics, and pH regulation. The study delves into the role of vaginal microenvironment dysregulation in the development of persistent HPV infection, multiple infections, and cervical lesions. It provides a research foundation for targeted interventions for the vaginal microenvironment in the elderly. The hope is that the discussions presented in this study can offer a more comprehensive and effective support framework for the health management of elderly women.