Abstract

Purpose: Total abdominal hysterectomy and bilateral salpingoophorectomy with pelvic and paraortic lymph node dissection remains the standard of care for the treatment of endometrial cancer. The value of specific adjuvant treatment modalities remains unclear. The PORTEC and GOG 99 trials showed a local control benefit for adjuvant pelvic radiation. When evaluating those with locoregional failure, most failed at the vaginal cuff. Therefore, vaginal cuff radiation has become increasingly more common, especially as morbidity is minimal. The length of vagina treated with high dose rate intracavitary brachytherapy has not been adequately investigated. The American Brachytherapy Society has recommended treating three to five centimeters length of vagina. Our institution has a long history of treating only the proximal one centimeter of vagina with high dose rate brachytherapy. The purpose of this study is to determine if treatment with only one centimeter active length is sufficient.

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