Abstract
1. 1. The proventriculi of White Leghorn cocks were acutely cannulated under sodium pentobarbital anesthesia. 2. 2. Electrical stimulation of the cervical vagi was found to be a potent stimulus for both acid and pepsin secretion. 3. 3. The threshold for vagal stimulation was found to be quite high (approximately 20 V), implying a very small fiber diameter for the nerves innervating the proventriculus. 4. 4. Peak outputs of acid and pepsin in response to vagal stimulation were 0·96 ± 0·05 m-equiv. H +/30 min and 103,500 ± 19,600 P.U./30 min, respectively. 5. 5. Ganglionic blockade with hexamethonium during continuous vagal stimulation inhibited both acid and pepsin secretion equally.
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