Vacunación universal contra la varicela – Observación sobre ciertos cuestionamientos

Abstract

In this article, the authors reviewed the current evidences for certain epidemiological observations published recently.In the mentioned publication, the investigator claims that universal varicella vaccination does not reduce varicella burden andincreases the long term risk of glioma by preventing natural infection with varicella zoster virus. The analysis of the evidencesshows that universal vaccination reduces morbidity, mortality, and hospitalization related to varicella. In contrast to investigator’s claim, moreover, the data demonstrate that universal vaccination does induce a herd effect.On the other hand, the available scientific information suggests that the association between natural infection with varicellazoster virus and lower risk of glioma is very weak and does not show causality. In this context one should entertain the idea ofany level of protection against glioma provided by natural infection with varicella zoster virus can be far outweighed by theimpact on morbidity and mortality caused by chickenpox.