Abstract

This report covers the topics of pandemics, epidemics and partnerships, including regulatory convergence initiatives, new technologies and novel vaccines, discussed by leading public and private sector stakeholders at the 18th Annual General Meeting (AGM) of the Developing Countries Vaccine Manufacturers’ Network (DCVMN). Contributions of Gavi and the vaccine industry from emerging countries to the growing global vaccine market, by improving the supply base from manufacturers in developing countries and contributing to 58% of doses, were highlighted. The Coalition for Epidemic Preparedness Innovations (CEPI), the International Vaccine Institute (IVI) and others reported on new strategies to ensure speedy progress in preclinical and clinical development of innovative vaccines for future MERS, Zika or other outbreak response. Priorities for vaccine stockpiling, to assure readiness during emergencies and to prevent outbreaks due to re-emerging diseases such as yellow fever, cholera and poliomyelitis, were outlined. The role of partnerships in improving global vaccine access, procurement and immunization coverage, and shared concerns were reviewed. The World Health Organization (WHO) and other international collaborating partners provided updates on the Product, Price and Procurement database, the prequalification of vaccines, the control of neglected tropical diseases, particularly the new rabies elimination initiative, and regulatory convergence proposals to accelerate vaccine registration in developing countries. Updates on supply chain innovations and novel vaccine platforms were presented. The discussions enabled members and partners to reflect on efficiency of research & development, supply chain tools and trends in packaging technologies improving delivery of existing vaccines, and allowing a deeper understanding of the current public-health objectives, industry financing, and global policies, required to ensure optimal investments, alignment and stability of vaccine supply in developing countries.

Highlights

  • The 18th Annual General Meeting of the Developing Countries Vaccine Manufacturers’ Network (DCVMN) gathered over 270 vaccine experts from 38 member-companies in emerging countries, 23 non-member companies and 28 non-industry organizations to inspire innovation and promote global access to vaccines

  • Torreele reported that Médecins sans Frontières (MSF) administered over 5 million vaccine doses in over 30 countries in 2015

  • Hatchett outlined the gap between late preclinical development and proof-of-concept studies in humans for outbreak vaccines that led to the launch of the Coalition for Epidemic Preparedness Innovation (CEPI) in January 2017

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Summary

Introduction

The 18th Annual General Meeting of the Developing Countries Vaccine Manufacturers’ Network (DCVMN) gathered over 270 vaccine experts from 38 member-companies in emerging countries, 23 non-member companies and 28 non-industry organizations to inspire innovation and promote global access to vaccines. The meeting, hosted by SK Chemicals and co-hosted by the International Vaccine Institute (IVI) in Seoul, South Korea, focused on pandemics, epidemics and partnerships. Q Report of the 18th annual general meeting of the developing countries vaccine manufacturers network, 25–27 September 2017, Seoul, Korea. S. Berkley reported that immunization coverage of DTP2containing vaccines has increased by 20%-points since the launch of Gavi support for poorest countries [2]. A recent project supported the introduction of Eubiologics’ new oral cholera vaccine to Gavi countries

Vaccine procurement and financing
Epidemic and pandemic vaccines
Innovative partnerships
Regulatory convergence initiatives
WHO prequalification updates
Innovative solutions for vaccine supply and distribution
Novel vaccines and technology platforms
Findings
Conclusion
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