Vaccine inoculation rate of hemorrhagic fever with renal syndrome in rural population and vaccination strategy in the Xi'an epidemic area

Abstract

Objective To describe the vaccine inoculation rate of hemorrhagic fever with renal syndrome (HFRS) and the movement characteristics of rural population in the Xi'an epidemic area. Methods This was a cross-sectional study. The study covered all the four HFRS traditional high incidence areas (counties): Zhouzhi, Huxian, Chang'an and Lintong. Three villages were selected in each county and 20 households were selected in each village in 2013. Participants included all the persons of these families. People 16-60 years old were interviewed face to face about their sociodemographic and environmental information, and at the same time related HFRS vaccine history and characters of migrant workers were collected. Results Nine hundred and ninety-six persons were investigated, 69.3 percent (690/996) were vaccinate-age population. Of all, 49.0 percent (338/690) had HFRS vaccine history and 53.9 percent (372/690) had worked away from home most of the year. The inoculation proportion of workers which worked in their own counties (56.8%, 67/118) were higher than that of workers worked outside (37.0%, 60/162; 39.1%, 36/92, χ2 = 10.74, 6.44, all P < 0.017). In the workers that went back home every week, 60.3 percent (76/126) had vaccinated. Workers that went back home once a year had the lowest proportion of inoculation (16.7%, 7/42). The morbidity of HFRS decreased significantly accompany with ascend of inoculation rate (Y=-0.524X + 38.319, t =-4.581, P < 0.05). Conclusions After the free vaccinations, there is still a gap between the vaccine inoculation rate and prevention benefit. The current vaccination strategies need to be adjusted. Key words: Hemorrhagic fever with renal syndrome; Vaccine; Inoculation rate