Vaccine Candidates for Arboviruses with Pandemic Potential: A Mini Review

Abstract

The increasing prevalence of arboviral diseases, driven by urbanization and travel, coupled with the absence of specific treatments or vaccinations, has led to a growing burden on global health. Despite the implementation of vector control programs, outbreaks continue to occur. While vaccines are considered the ultimate solution, progress in the development of vaccines for dengue virus, Zika virus, Chikungunya virus, and West Nile virus has been limited, due to factors such as limited access to target populations, lack of funding, and concerns about safety and efficacy across all age groups. Furthermore, the growing trend of vaccine hesitancy presents a significant barrier to future vaccine adoption. This review provides a subtle overview of current progress in the development of vaccine candidates for these prevalent arboviral diseases.