Abstract

The “Vaccine and Drug Ontology Studies” (VDOS) international workshop series focuses on vaccine- and drug-related ontology modeling and applications. Drugs and vaccines have been critical to prevent and treat human and animal diseases. Work in both (drugs and vaccines) areas is closely related - from preclinical research and development to manufacturing, clinical trials, government approval and regulation, and post-licensure usage surveillance and monitoring. Over the last decade, tremendous efforts have been made in the biomedical ontology community to ontologically represent various areas associated with vaccines and drugs – extending existing clinical terminology systems such as SNOMED, RxNorm, NDF-RT, and MedDRA, developing new models such as the Vaccine Ontology (VO) and Ontology of Adverse Events (OAE), vernacular medical terminologies such as the Consumer Health Vocabulary (CHV). The VDOS workshop series provides a platform for discussing innovative solutions as well as the challenges in the development and applications of biomedical ontologies for representing and analyzing drugs and vaccines, their administration, host immune responses, adverse events, and other related topics. The five full-length papers included in this 2014 thematic issue focus on two main themes: (i) General vaccine/drug-related ontology development and exploration, and (ii) Interaction and network-related ontology studies.

Highlights

  • Introduction and backgroundDrugs and vaccines have been critical to prevent and treat human and animal diseases

  • Work in both areas is closely related - from preclinical research and development to manufacturing, clinical trials, government approval and regulation, and post-licensure usage surveillance and monitoring

  • Vaccine and Drug Ontology Studies (VDOS) 2014 was held on October 7, 2014, in Houston, Texas

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Summary

Introduction

Introduction and backgroundDrugs and vaccines have been critical to prevent and treat human and animal diseases. The 2014 “Vaccine and Drug Ontology Studies” workshop (VDOS 2014) was an international forum for researchers to identify, propose, and discuss solutions for important research problems in ontology representation and analysis of vaccine and drug development, administration, function mechanisms, safety, and education. This workshop was part of the Fifth International Conference on Biomedical Ontology (ICBO 2014).

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