Abstract
GENERAL COMMENTARY article Front. Immunol., 03 February 2014Sec. Vaccines and Molecular Therapeutics https://doi.org/10.3389/fimmu.2014.00032
Highlights
Vaxjo: a web-based vaccine adjuvant database and its application for analysis of vaccine adjuvants and their uses in vaccine development by Sayers S, Ulysse G, Xiang Z, He Y. (2012)
We have previously described the “vaccine informatics” that focuses on the development and application of bioinformatics methods for facilitating different aspects of preclinical vaccine research and development, clinical vaccine trials, and post-licensure vaccine safety and efficacy surveillance (1)
Vaccine adjuvant informatics addresses scientific questions different from those associated with the whole vaccines or other vaccine components
Summary
Vaxjo: a web-based vaccine adjuvant database and its application for analysis of vaccine adjuvants and their uses in vaccine development by Sayers S, Ulysse G, Xiang Z, He Y. (2012). A vaccine adjuvant is a vaccine component that is used to enhance host immune responses to the antigens in the vaccine. While live attenuated vaccines without adjuvants often stimulate strong immune responses, they are difficult to be approved for human use due to potential safety concerns.
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