Abstract
Atypical furunculosis caused by atypical Aeromonas salmonicida is an increasing problem in commercial halibut farming, and a potential problem in farming of spotted wolffish in Norway. Halibut, Hippoglossus hippoglossus L., and spotted wolffish, Anarhichas minor L., vaccinated with oil-emulsified vaccines against atypical furunculosis, demonstrated a relative percent survival (RPS) of approximately 90 when challenged with homologous isolates. Bath and aqueous injection vaccines failed to protect against disease when challenged 10 weeks post-vaccination. High antibody titres were produced in both species after vaccination with oil-emulsified vaccines, and the major antibody response were against A-layer, LPS and some minor outer membrane (OM) proteins.
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