Abstract

ObjectiveTo support efforts to address parental hesitancy towards early childhood vaccination, we sought to validate the Vaccination Confidence Scale using data from a large, population-based sample of U.S. parents.MethodsWe used weighted data from 9,354 parents who completed the 2011 National Immunization Survey. Parents reported on the immunization history of a 19- to 35-month-old child in their households. Healthcare providers then verified children’s vaccination status for vaccines including measles, mumps, and rubella (MMR), varicella, and seasonal flu. We used separate multivariable logistic regression models to assess associations between parents’ mean scores on the 8-item Vaccination Confidence Scale and vaccine refusal, vaccine delay, and vaccination status.ResultsA substantial minority of parents reported a history of vaccine refusal (15%) or delay (27%). Vaccination confidence was negatively associated with refusal of any vaccine (odds ratio [OR] = 0.58, 95% confidence interval [CI], 0.54–0.63) as well as refusal of MMR, varicella, and flu vaccines specifically. Negative associations between vaccination confidence and measures of vaccine delay were more moderate, including delay of any vaccine (OR = 0.81, 95% CI, 0.76–0.86). Vaccination confidence was positively associated with having received vaccines, including MMR (OR = 1.53, 95% CI, 1.40–1.68), varicella (OR = 1.54, 95% CI, 1.42–1.66), and flu vaccines (OR = 1.32, 95% CI, 1.23–1.42).ConclusionsVaccination confidence was consistently associated with early childhood vaccination behavior across multiple vaccine types. Our findings support expanding the application of the Vaccination Confidence Scale to measure vaccination beliefs among parents of young children.

Highlights

  • From January 2014 to June 2015, the Centers for Disease Control and Prevention documented over 800 cases of measles in the United States, including a cluster of 117 cases linked to a California amusement park [1]

  • Vaccination confidence was consistently associated with early childhood vaccination behavior across multiple vaccine types

  • Our findings support expanding the application of the Vaccination Confidence Scale to measure vaccination beliefs among parents of young children

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Summary

Introduction

From January 2014 to June 2015, the Centers for Disease Control and Prevention documented over 800 cases of measles in the United States, including a cluster of 117 cases linked to a California amusement park [1]. Public health research to date largely supports assertions made in the popular press that parents’ confidence in routine vaccination has eroded in recent years, leading to vaccine refusal and delay [3,4,5,6]. Neither vaccine refusal and delay, nor the underlying concerns that motivate these behaviors, are routinely assessed in the National Immunization Survey or other ongoing, large-scale surveillance efforts. For this reason, our ability to more directly quantify changes in the prevalence of vaccine hesitancy is limited

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