Abstract
The review discusses the current state of the use of vaccine prevention in the debarment of pneumococcal infection in patients with chronic kidney disease (CKD). Clinical and immunological features of various groups of patients with chronic kidney disease are considered, the specifics of their immunoreactivity, the features of their immune system, due to the underlying and concomitant diseases, as well as treatment. The review analyzes data on various approaches to preventive vaccination and discusses the results of various vaccination regimens and vaccines. Based on the materials reviewed, recommendations are given for organizing the most rational vaccine prevention of pneumococcal infection in patients with chronic kidney disease.
Highlights
The review discusses the current state of the use of vaccine prevention in the debarment of pneumococcal infection in patients with chronic kidney disease (CKD)
Что в современных рекомендациях для взрослых с хронической болезнью почек и с нефротическим синдромом предусмотрена профилактика пневмококковой инфекции, за последние пять лет только 22% больных, находящихся на диализе, оказались привиты [37, 38, 63, 64]
Summary
The review discusses the current state of the use of vaccine prevention in the debarment of pneumococcal infection in patients with chronic kidney disease (CKD). Пациенты с хроническими заболеваниями почек могут иметь как врожденные, так и приобретенные нарушения иммунитета, например, в пожилом возрасте, при хронической почечной недостаточности или назначении иммуносупрессивной терапии.
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