Éva Tóth;

Abstract

Angewandte Chemie International EditionVolume 58, Issue 2 p. 374-374 Author ProfileFree Access Éva Tóth; First published: 05 September 2018 https://doi.org/10.1002/anie.201809467AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract “My favorite food is Hungarian pastries made with cottage cheese or poppy seeds. If I were not a scientist, I would do something related to literature …” Find out more about Éva Tóth in her Author Profile. Éva Tóth The author presented on this page was one of the recipients of the CNRS Silver Medals 2018. More information about the award can be found at: Angew. Chem. Int. Ed. 2018, 57, 6382; Angew. Chem. 2018, 130, 6490. Date of birth: June 14, 1967 Position: CNRS Research Director, Centre of Molecular Biophysics, Orléans E-mail: eva.jakabtoth@cnrs-orleans.fr Homepage: http://cbm.cnrs-orleans.fr/spip.php?article7131 ORCID: 0000-0002-3200-6752 Education: 1990 Chemistry degree, University of Debrecen 1994 PhD supervised by Prof. Ernő Brücher, University of Debrecen 1995–1999 Postdoctoral position with Prof. André E. Merbach, Université de Lausanne Awards: 2018 CNRS Silver Medal Research: MRI contrast agents, responsive probes, coordination chemistry for biomedical applications Hobbies: Literature, cooking My favorite food is Hungarian pastries made with cottage cheese or poppy seeds. If I were not a scientist, I would do something related to literature. When I'm frustrated, I try to occupy myself with some simple physical work like gardening or cleaning the house. You can always see an immediate and concrete result (even if not long-lasting). The two most important things I learned from my parents are to persevere and to appreciate also small, simple things in life instead of only waiting for your greatest dreams to come true. If I could have dinner with three famous scientists from history, they would be first of all Marie Curie and then chemists from the 18th/19th century such as Lavoisier and Mendeleev. It is impressive to consider their discoveries made without sophisticated instrumentation. And I would be too intimidated to ask anything. I hope they would talk without me asking them. My best investment was the time I spent with my children. The most exciting thing about my research is to discover unexpected chemical behavior and then to explain and to exploit it, and all this in a team effort. My favorite authors (fiction) are Lev Tolstoy, Stefan Zweig, Boris Pasternak, and many others. My favorite piece of music is Tchaikovsky's Violin Concerto. My favorite motto is “Think like a proton. Stay positive”. My 5 top papers: 1“Gd(DTPA-bisamide)alkyl Copolymers: A Hint for the Formation of MRI Contrast Agents with Very High Relaxivity”: É. Tóth, L. Helm, K. Kellar, A. E. Merbach, Chem. Eur. J. 1999, 5, 1202. (Rotational dynamics were described in terms of local and global motions by analyzing variable-field relaxation rates. This approach is widely used today for the characterization of nanosized MRI probes.) 2“Detection of Enzymatic Activity by PARACEST MRI: A General Approach to Target a Large Variety of Enzymes”: T. Chauvin, P. Durand, M. Bernier, H. Meudal, B.-T. Doan, F. Noury, B. Badet, J.-C. Beloeil, É. Tóth, Angew. Chem. Int. Ed. 2008, 47, 4370; Angew. Chem. 2008, 120, 4442. (A self-immolative platform that can be adapted for the detection of many different enzymes.) 3“Pyridine-Based Lanthanide Complexes Combining MRI and NIR Luminescence Activities”: C. S. Bonnet, F. Buron, F. Caillé, C. M. Shade, B. Drahoš, L. Pellegatti, J. Zhang, S. Villette, L. Helm, C. Pichon, F. Suzenet, S. Petoud, É. Tóth, Chem. Eur. J. 2012, 18, 1419. (Despite the presence of two inner-sphere water molecules in a complex, it is still possible to observe the luminescence of NIR-emitting lanthanides.) 4“MRI sensing of Neurotransmitters with a Crown Ether Appended Gd3+ Complex”: F. Oukhatar, S. Même, W. Même, F. Szeremeta, N. K. Logothetis, G. Angelovski, É. Tóth, ACS Chem. Neurosci. 2015, 6, 219. (Visualization of neurotransmitter release in a brain slice MRI experiment using a Gd3+-based MRI agent.) 5“Prototypes of Lanthanide(III) Agents Responsive to Enzymatic Activities in Three Complementary Imaging Modalities: Visible/Near-Infrared Luminescence, PARACEST- and T1-MRI”: J. He, C. S. Bonnet, S. V. Eliseeva, S. Lacerda, T. Chauvin, P. Retailleau, F. Szeremeta, B. Badet, S. Petoud, É. Tóth, P. Durand, J. Am. Chem. Soc. 2016, 138, 2913. (A single ligand, when complexed to different lanthanide ions, can provide enzyme-responsive probes detectable by three different imaging techniques.) Volume58, Issue2January 8, 2019Pages 374-374 ReferencesRelatedInformation