UV-induced red fluorescence on facial part of patients with acne vulgaris and seborrheic dermatitis: a fluorescence spectrum study

Abstract

Objective To measure the fluorescence spectral information of UVRF in the facial skin of patients with acne vulgaris and seborrheic dermatitis and to comprehend the optical properties of UVRF. Methods The lesions were squeezed to extract the sebaceous secretions containing UVRF in the facial skin. Ocean Optics USB2000+ F02243 Spectrometer and the 308nm excimer laser were used as an excitation light source to measure the signal of the LIF spectrum of UVRF in 6 acne vulgaris and 4 seborrheic dermatitis patients' facial part, compared with protoporphyrin Ⅸ. Results 1-4 peaks were detected in 10 patients' UVRF specimen respectively. The fluorescence spectra's characteristic peak of UVRF in 10 patients was at 680 nm. Protoporphyrin Ⅸ was at 688 nm and more gentle and generous than UVRF's characteristic peak. Conclusions LIF system can be used to detect the fluorescence spectroscopy of UVRF. UVRF has similar spectral characteristics to protoporphyrin Ⅸ, but it is not the same species. Key words: Acne; Seborrheic dermatitis; Fluorescence spectrum; Red fluorescence; Laser induced fluorescence