Abstract
This chapter will present evidence that UV-enhanced reactivation (ER) of SV40 is due to the restoration of viral early gene function. The observation supporting this conclusion is, simply, that ER acts only on damage in the viral early gene region; lesions elsewhere in the SV40 genome are not subject to ER. The implication of this finding is that cells respond to UV-induced damage by inducing the ability to synthesize RNA from a damaged DNA template.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
