Abstract

Two different species Streptomyces aureofaciens and S. albidoflavus were collected from Microbial Type Culture Collection Centre, Chandigarh, India. These two species were extensively studied for their in vitro anticandidial activity. The result indicated that S. aureofaciens was highly active against Candida albicans. The UV spectral analysis of the produced antifungal metabolite of S. aureofaciens and S. albidoflavus showed the absorbance peaks at 240nm. The FTIR spectral study revealed that the ethyl acetate extracts of S. aureofaciens and S. albidoflavus fermentation broth exhibited absorption from 2956 to 2360.7cm -1 and from 3310 to 2358.8cm -1 , respectively, which indicate hydroxyl groups and absorption at 1639 cm -1 indicating a double bond of non polyenic compound.

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