Abstract
To develop an anticoagulant coating for polyethylene terephthalate (PET) fabric-covered stents, we prepared a series of ultraviolet (UV)-curable coatings with different film-forming compositions and enoxaparin sodium ratios. We then investigated their mechanical properties and hydrophilicity by adhesion, pencil hardness, abrasion resistance tests, and water contact angle measurements. In addition, their biocompatibility and cytotoxicity were evaluated by their protein adsorption, platelet adhesion, and plasma recalcification times, and by CCK-8 assays. Finally, an anticoagulant coating with excellent mechanical properties, biocompatibility, and low cytotoxicity was obtained, offering a feasible scheme for covered stents in clinical practice.
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