Abstract
Physiological stress for a long time can lead to impaired kidney organ function. Snakehead fish meat are known to contain important nutrients such as albumin, glutamine, glycine, cysteine, and various minerals that can improve kidney function. This study was conducted to examine and analyze the effect of snakehead fish supplementation in feed towards body weight, kidney weight, diameter and number of glomerulus in Wistar rats with physiological stress. This study used 20 male Wistar rats divided into 5 groups consisted of 1 control group (P0) and 4 treatment groups (P1: 5%, P2: 10%, P3: 15%, P4: 20%). The treatments were performed with 4 times repetition. This study used Completely Randomized Design (CRD). The variables measured were body weight, kidney weight, diameter and number of renal glomerulus. The data obtained were analyzed using Analysis of Variance (ANOVA) at 5% significance level and continued with Duncan test with 5% significance level. The results of this study were: the supplementation of snakehead fish with 20% of concentration can increase the body weight; concentration 10; 15; and 20% can increase the weight of the kidney; concentrations of 5%, 10%, 15%, and 20% can increase the glomerular diameter in Wistar rats with physiological stress. The supplementation of snakehead fish with concentration of 5% to 20% did not affect the number of glomerulus of Wistar rats with physiological stress. Results of this study is useful as information for people who study the mechanism of kidney repair due to physiological stress.
Highlights
Proper nutrition intake can improve the functioning of the body’s defense system, so as to lower the physiological stress level and susceptibility to a disease
Based on the background of the research that has been described, this study aimed to find out the influence of snakehead fish meat supplementation in the feed towards the body weight, weight of the kidney as well as the diameter, and the number of glomerulus in Wistar rats with physiological stress triggered by nutritional deficiencies and excessive physical stress
The data of this study showed that supplementation of snakehead fish meat mixed into feed with a concentration of 10; 15; and 20% could increase the kidney weight of rats that experienced physiological stress with the highest values found in P2 and P3, respectively 0.95 g and 0.94 g and the is P4 of 0.88 g
Summary
Proper nutrition intake can improve the functioning of the body’s defense system, so as to lower the physiological stress level and susceptibility to a disease. Malnutrition can lead to changes in body composition, such as the amount and distribution of fluids, fats, minerals, and proteins, especially muscle protein. Malnutrition conditions can trigger a decrease in the body’s total potassium level, especially in cell, causing metabolic disorders in organs such as the kidneys, muscles, and pancreas. Abnormalities of organs often occur such as the upper alimentation system (mouth, tongue, neck), gastrointestinal system (liver, pancreas), heart, kidney, endocrine system, so that malnutrition conditions must be handled quickly, precisely, and meticulously (Sunarno et al, 2016). Malnutrition accompanied by excessive physical activity can cause physiological stress in the body that has the potential to trigger the occurrence of various disorders of the organs of the body
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