Utilization of Probiotic Bacteria Enterococcus lactis for Biogenic Synthesis of Hemocompatible AgNPs

Abstract

Fermented food and beverages have potential novel Probiotic microorganism which possess many beneficial role in human health and hygiene. The tribal people consume variety of locally produced fermented food and beverages regularly and hence their gut microflora are strongly benefited. Mayurbhanj district in Odisha, India is diversified with many tribal population. Handia, is the most preferred fermented rice beverage in the tribal community having cultural, religious and social values associated with it. Recent advances in the fields of science like nanoscience and nanotechnology have radically changed the way we diagnose, treat, and prevent various diseases in all aspects of human life. This current investigation was undertaken to explore the various possibilities to screen the potentiality of utilizing Enterococcus lactis, a probiotic bacteria isolated from the fermented rice beverage “Handia” in terms of their efficacy for synthesis of Silver nanoparticles (AgNPs). The synthesized AgNPs were screened through Fe-SEM, EDS, XRD, FTIR, DLS and UV-visible spectroscopy characterization studies. The synthesized AgNPs exhibited enhanced antioxidant, antimicrobial and anti-biofilm forming capability. Understanding the implications of green-synthesized AgNPs from probiotic bacteria would help in designing and delivery of bioactive components present in probiotic microorganism for future drug delivery application and other nanoparticle based therapeutics in different sectors of biomedical engineering and technology.