Abstract

Emission computed tomography (ECT) has gained recognition in the past decade as a valuable tool in nuclear medicine imaging. The ECT falls into one of two categories: positron ECT and single-photon ECT(SPECT)[1]. The ECT has the advantage of higher object contrast than planar imaging, but at the same time has often suffered from a lack of sufficient count densities to achieve statistically smooth images. The poor counting statistics is due to limited isotope dosage to patients, limited counting time and limited count rate capability of the imaging devices. Fast dynamic studies require reduction of total number of counts to be accumulated per image, and high resolution imaging further reduces count density per resolution cell. The magnitude of statistical noise of an image depends on various factors such as the radionuclide distribution, the total number of counts, the number of resolution cells in the object area, etc., but it also depends on the reconstruction algorithm, because the statistical noise is amplified in the stage of image reconstruction.

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