Abstract
4536 Background: While tandem autografts are commonnly used to treat pts with advanced testes cancer, their value vs a single transplant is unknown. Methods: We performed a retrospective cohort analysis of all cases with detailed research data reported to the ABMTR between 1989–2001. Outcomes were analyzed by the actual number of transplants performed and by “intent to treat” for single vs tandem trasnplants. To remove waiting time bias for second transplant, calculations were based on pts alive at 4.3 mos, the longest time between 1st and planned 2nd transplant. Results: A total of 303 pts were reported; 259 were analyzed. Their median age was 32; median time from diagnosis to first transplant was 13 mos and median f/u of survivors was 62 months. Of the 259, 165(64%) underwent one planned transplant, 81 (31%) tandem transplants and 13(5%) underwent only one of two planned transplants. Of pts with non-seminoma, 19, 14 and 33% were in the good, intermediate and poor risk International Prognostic Score grou...
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