Abstract
Positron emission tomography (PET) using fluorine-18 (FDG) is increasingly used in the staging of lymphoma. Results of the use of PET during and after completion of therapy for staging of Hodgkin’s lymphoma and aggressive non-Hodgkin’s lymphoma demonstrate a highly predictive value for outcome. Based on recommendations of the International Harmonization Project, FDG-PET has been incorporated into the revised response criteria of lymphoma. There is currently no evidence to support the use of FDG-PET in indolent lymphoma, nor for its routine use during follow-up. Evidence also lacks on the impact of FDG-PET on treatment outcome. Clearly, well designed clinical trials are warranted to determine the subsets of patients that will benefit from this modality.
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