UTILITY OF FNAC IN THE EVALUATION OF BREAST LESIONS WITH HISTOPATHOLOGICAL CORRELATION

Abstract

Introduction: Most of the women with breast pathology present as lump in their breast. Malignancy of Breast is the most common problem with increasing incidence in females. Early diagnosis and appropriate treatment of a breast lump is lifesaving. Fine-Needle Aspiration Cytology (FNAC) is a simple, safe, inexpensive method with wide acceptance and used as a rst-line diagnostic procedure for diagnosis of breast lesions. The main aim of the study w Aim: as to diagnose any palpable lump of the breast in females by FNAC technique and to correlate with histopathology reports. This was a retrospe Setting and Design: ctive study done out in the Department of Pathology, Kurnool Medical College, Kurnool. Study period was for 2 years (January 2021 to De Materials and Methods: cember 2022). For all breast lumps FNAC was done, processed; Haematoxylin and Eosin stain and Papanicolaou stain was done wherever necessary. For same patients who ever undergone Tru-cut biopsies, excisional biopsies, and surgical specimens were received and histopathological correlation was done. Data was collected and entered in MS excel sheet. The sensitivi Statistical Analysis: ty, specicity, positive predictive value, negative predictive value, and accuracy were calculated. Among 531 cases, 426(80.22%) were benign Results: and 105(19.77%) were malignant on cytology. Out of this, 215(40.48%) cases underwent histopathological examination, in which 118(54.88%) were benign and 97(45.11%) were malignant cases. The sensitivity, specicity, positive predictive value, negative predictive value, and accuracy of the present study were 84.82%, 98.05%, 97.93%, 85.59%, and 91.96% respectively. The FNAC is the common and most important prelimi Conclusion: nary diagnostic test in palpable breast lumps and there was high degree of correlation with a nal histopathological report