Abstract
Severe rectal bleeding is a rare complication of chronic radiation proctitis (CRP). Given CRP's propensity to involve the full thickness of the rectal tissue, we proposed that endoscopic full-thickness resection may be a successful therapeutic modality for treating CRP. A 76-year-old man with multiple comorbid conditions who was not a surgical candidate presented with severe bleeding secondary to CRP that was refractory to all medical and therapeutic interventions. An endoscopic full-thickness resection was performed, which initially resulted in hemostasis, but the patient ultimately developed recurrent rectal bleeding, and endoscopic resection was determined to be unsuccessful.
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